HPLC Column, HPS Silica, 5um, 2.1mm ID x 150mm Length, 120A. Cogent Brand. 1 EA.
Additional Info:
75001-15P-2 Cogent HPS Silica™ HPLC Column is packed with high‑purity, unmodified silica, providing reliable and reproducible performance for normal phase chromatography and USP L3 classified methods.
Because the stationary phase is not chemically modified, it enables strong, direct interactions with polar and hydrophilic compounds, making it particularly effective for fats, lipids, and other polar analytes.
This proprietary HPS Silica™ has been widely used in HPLC laboratories for many years as a premium-value, dependable alternative to commonly used silica columns such as Inertsil® and Luna®, offering consistent selectivity and performance.
The 5 µm particle size provides a practical balance between efficiency and durability, allowing higher flow rates with lower backpressure compared to smaller particle columns, making it ideal for routine analytical applications.
150 mm Length – High Resolution Normal Phase Separations
The 150 mm column length provides increased resolving power for more challenging separations.
Higher resolution than 50 mm and 100 mm formats
Improved separation of closely related compounds
Increased peak capacity for complex samples
✅ Recommended for applications requiring maximum resolution in normal phase HPLC
2.1 mm ID – Low‑Flow Analytical Format
Designed for 2.1 mm ID analytical columns
Reduced solvent consumption
Ideal for LC‑MS compatible workflows
Maintains sensitivity in low‑dispersion systems
✅ Recommended for labs prioritizing solvent savings and high-efficiency separations
Flow Rate & System Requirements (2.1 mm ID, 5 µm)
⚠️ Requires low‑flow capable HPLC or UHPLC system
Typical flow rate range: ~0.2 – 0.4 mL/min
Lower backpressure vs smaller particle sizes
Suitable for standard HPLC systems with low‑flow capability
Compatible with UV and MS detection
✅ Important: Ensure system can deliver stable and precise low‑flow operation
Why Choose HPS Silica™ Columns
High‑Purity Unmodified Silica
Ideal for normal phase chromatography
Strong retention of polar compounds
USP L3 Compatibility
Suitable for compendial and regulated methods
Reliable alternative to legacy silica phases
Consistent Performance
Reproducible selectivity batch‑to‑batch
Proven reliability in long‑term use
Performance Advantages
Lower Backpressure (5 µm Particles)
Enables routine operation on standard HPLC systems
Supports moderate flow rates
Fast Equilibration
Reduces downtime between runs
Enhanced Polar Retention
Ideal for hydrophilic compounds, fats, and lipids
Typical Applications
Fats and lipid analysis
Complex normal phase separations
Polar compound analysis
USP L3 method development and validation
Food, pharmaceutical, and chemical testing
Important Usage Notes
Designed for normal phase chromatography conditions
Use appropriate non‑polar mobile phases
Ensure proper equilibration for reproducible results
Follow standard silica column handling and storage practices